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C57BL/6 Mouse Lung Fibroblasts

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Product Name

C57BL/6 Mouse Lung Fibroblasts

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Cat.No

ABC-TC3212

Species

C57BL/6 Mouse

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Mouse lung fibroblasts (MLUFC) are isolated from tissue of pathogen-free laboratory mice. Mouse lung fibroblasts are grown in T75 tissue culture flasks pre-coated with 0.2% gelatin for 0.5 hour and incubated in Culture Complete Growth Medium generally for 3-7 days.

Disease

Normal

Source Organ

Lung

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

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Application

For research use only

Growth Conditions

37 ℃, 5% CO2

Cell Type

Fibroblast

Growth Mode

Adherent

Product Type

Mouse Primary Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial

Frequently Asked Questions

  • What are C57BL/6 Mouse Lung Fibroblasts?

    C57BL/6 Mouse Lung Fibroblasts are specialized fibroblast cells derived from the lung tissue of C57BL/6 mice. They play a key role in maintaining the structural integrity of lung tissue by producing extracellular matrix proteins and supporting the repair and remodeling processes in response to injury.

  • What are the primary functions of C57BL/6 Mouse Lung Fibroblasts?

    The main functions of these fibroblasts include synthesizing extracellular matrix components like collagen and elastin, which maintain lung tissue architecture. They also play a significant role in wound healing, fibrosis, and lung tissue repair, especially after injury or inflammation.

  • How are lung fibroblasts involved in the development of pulmonary fibrosis?

    In pulmonary fibrosis, these fibroblasts become activated and differentiate into myofibroblasts, which produce an excess of extracellular matrix proteins. This leads to scarring or fibrosis in the lung, resulting in impaired respiratory function and lung stiffness.

  • What are C57BL/6 Mouse Lung Fibroblasts used for in research?

    These cells are utilized in research focused on lung tissue repair, fibrosis, inflammation, and wound healing. They are also used in drug discovery for developing therapies targeting lung diseases, including treatments aimed at reducing fibrotic tissue formation.

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