COR-L24

The COR-L24 cell line, originating from a lymph node biopsy of an untreated 71-year-old male diagnosed with small cell lung carcinoma (SCLC), serves as a valuable model in biomedical research. Derived from a xenograft forming culture, this cell line manifests as floating aggregates of densely packed cells with irregular shapes, representing the characteristic features of SCLC.

The COR-L24 cell line, established and characterized in 1985, COR-L24 cells maintain classic neuroendocrine properties synonymous with SCLC. Notably, the patient’s bone marrow, while hypercellular and indicative of normal hematopoietic cells, exhibited no evidence of neoplasm.

The well-documented history and neuroendocrine characteristics of COR-L24, coupled with its establishment from an untreated SCLC patient, position it as a representative and valuable tool for studying the pathobiology, therapeutic responses, and molecular aspects of small cell lung carcinoma.

Why choose ABC-TC0180 COR-L24 from AcceGen?

Elevate your studies with confidence, knowing that each AcceGen’s COR-L24 cell line undergoes rigorous quality control (QC) tests, ensuring the utmost reliability in your experiments.

Key Quality Control Measures:

Sterility Assurance:

COR-L24 cells are subjected to thorough testing to confirm negative results for bacterial, fungal, and mycoplasma contamination. Utilizing advanced PCR techniques, we ensure a sterile and uncontaminated cell culture environment. Additionally, the cells are verified to be free from human pathogens.

Identity Verification with STR Analysis:

Upholding the highest standards of authenticity, we conduct Short Tandem Repeat (STR) analysis using 16 probes, encompassing 15 STR loci plus Amelogenin. This rigorous identity check ensures the unequivocal authenticity of the COR-L24 cell line.

Morphology and Marker Expression Analysis:

COR-L24 cells exhibit growth characteristics meticulously assessed based on morphology and immunocytochemistry of multiple undifferentiation markers. This comprehensive evaluation ensures that COR-L24 maintains its intended properties for your research needs.