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Human Cardiac Fibroblasts |
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| Product Name |
Human Cardiac Fibroblasts |
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| Price | Get Quote | |||
| Product Code | HCF |
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| Cat.No |
ABC-TC3533 |
Species |
Human |
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| Size/Quantity |
1 vial |
Biosafety Level |
1 |
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| Shipping Info |
Dry Ice |
Storage |
Liquid Nitrogen |
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| Description |
Human Cardiac Fibroblasts (HCFs) are isolated from heart tissue, providing structural support for cardiac myocytes. HCF is one of the major cellular components in the heart, participating in heart function, homeostasis, and structure. Cardiac fibroblast cells secrete collagen and play a role in providing structural support for the heart. The cardiac fibroblast cell proliferation and synthesis of matrix are vital to scar formation in myocardial infarction and cardiac fibrosis. However, inappropriate cardiac fibroblast proliferation is a causative factor in cardiac fibrosis. Why Choose HCF from AcceGen? |
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| Disease | Normal |
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| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
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| Recommended Medium And Supplement | ABM-TM3533 Human Cardiac Fibroblasts Medium Kit |
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| Citation Guide |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). |
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| Application | For research use only Cardiac fibroblast culture has been widely applied in studying the remodeling of the cardiac matrix by physiological (exercise) and pathological (hypertension) stressors. Cardiac fibroblast model is excellent to study extracellular matrix producing and remodeling, as well as myocardial responses to injury like wounds, toxicology and pathology. Suitable to establish serum-free human feeder layers for human embryonic stem cell cultures. |
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| Key Features | -Backed by AcceGen advanced technology |
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| Growth Conditions | 37 ℃, 5% CO2 |
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| Cell Type | Fibroblast |
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| Growth Mode | Adherent |
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| Product Type |
Cardiac Cells |
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| Product Image |
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Frequently Asked Questions
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What are Human Cardiac Fibroblasts?
Human Cardiac Fibroblasts are specialized cells found in the connective tissue of the heart. They play a crucial role in maintaining the structural integrity of the heart by producing and remodeling the extracellular matrix, which supports cardiac muscle cells and blood vessels.
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What are the primary functions of Human Cardiac Fibroblasts?
The primary functions of these fibroblasts include the synthesis and regulation of the extracellular matrix, which maintains the structure of the heart. They also play a critical role in the repair and remodeling of heart tissue following injury, such as myocardial infarction.
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What are Human Cardiac Fibroblasts used for in research?
Human Cardiac Fibroblasts are used in studies related to cardiac repair, fibrosis, heart failure, tissue engineering, and drug development. They are crucial in developing therapies that aim to prevent or reverse fibrosis and other pathological changes in the heart.
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What factors influence the activation of Human Cardiac Fibroblasts?
The activation of Human Cardiac Fibroblasts is influenced by factors like mechanical stress, inflammatory cytokines (e.g., TGF-β), and signals from injured cardiac tissue. These factors can lead to fibroblast-to-myofibroblast transformation, which contributes to the excessive production of extracellular matrix and fibrosis.
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