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Human Pancreatic Type 1 Diabetic Islets of Langerhans |
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| Product Name |
Human Pancreatic Type 1 Diabetic Islets of Langerhans |
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| Price | Get Quote | |||
| Cat.No |
ABC-H0093X |
Species |
Human |
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| Size/Quantity |
1 vial |
Biosafety Level |
1 |
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| Shipping Info |
Dry Ice |
Storage |
Liquid Nitrogen |
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| Description |
The Human Pancreatic Type 1 Langerhans Cells was derived from Human Pancreas. Each vial contains at least 1×10^6 cells per ml and is delivered frozen. |
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| Disease | Type 1 Diabetic |
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| Source Organ | Islet |
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| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
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| Recommended Medium And Supplement | ABM-H0093X Human Pancreatic Type 1 Diabetic Islets of Langerhans Medium Kit |
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| Citation Guide |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). |
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| Application | For research use only |
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| Growth Conditions | 37 ℃, 5% CO2 |
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| Cell Type | Islets of Langerhan |
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| Growth Mode | Adherent |
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| Product Type |
Pancreatic Cells |
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| Product Image |
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Frequently Asked Questions
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What are Human Pancreatic Type 1 Diabetic Islets of Langerhans, and how are they obtained?
These are clusters of pancreatic cells isolated from individuals with Type 1 Diabetes. They include beta cells, which are responsible for insulin production, and are typically obtained from donor pancreatic tissue through enzymatic digestion and density gradient centrifugation.
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What are primary research applications for Human Pancreatic Type 1 Diabetic Islets of Langerhans?
These islets are used in research focused on Type 1 Diabetes, including studies on insulin production, beta-cell function and regeneration, autoimmune mechanisms, and the development of new diabetes treatments.
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How do Human Pancreatic Type 1 Diabetic Islets of Langerhans differ from non-diabetic islets?
In Type 1 Diabetes, the beta cells in the islets are damaged or destroyed by an autoimmune response, leading to reduced or absent insulin production. This is a key difference compared to non-diabetic islets, which have functioning beta cells.
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Can Human Pancreatic Type 1 Diabetic Islets of Langerhans be passaged in culture?
No, Human Pancreatic Type 1 Diabetic Islets of Langerhans cannot be passaged in culture. These are primary cells with a limited lifespan, and they do not proliferate like cell lines. Once isolated, the islets can be maintained in culture for a limited period to study their function, but they will not divide or generate new islets. For ongoing studies, new islets must be isolated from donor tissue.
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